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KMID : 0360219730140040011
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Journal of the Korean Ophthalmological Society
1973 Volume.14 No. 4 p.11 ~ p.16
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Experimental Studies on the vitreous Substitutes
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Abstract
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Experimental replacements of rabbit vitreous by air, normal saline, dextran and Haemaccer were fried in albino rabbits. After aspiiation of 0.7ml of liquid vitreous from the central portion of vitreous, 0.5m1 of substitutes were injected. Clinically, these substitutes were well tolerated with slight uveal inflammation which subsided within one week. Intraocular pussure returned to normal value after 5 days.
Hexosamine content of the whole vitreous samples showed moderate increase after"Haemaccel injection which decreased slowly thereafter, whereas no significant changes were observed with other substitutes.
Hydroxyproline content of the whole vitreous also showed marked increase after injection of Haemaccel, owing to the high hydroxyproline content of Haemaccel. After 6 weeks 22.9% of the injected hydroxyproline remained in the vitreous. With other substitutes no change was observed.
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